Krasnov A.V.

SOME THERMODYNAMIC CHARACTERISTICS OF «THIOMEBICAR» (2,4,6,8-TETRAMETHYLDITHIOGLYCOLURIL)

DOI: 10.6060/tcct.20165912.5458
Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol. 2016. V. 59. N 12. P. 40-44.

Using the differential scanning calorimetry and mass spectrometry (in combination with a Knudsen effusion method), the enthalpies of fusion and sublimation for the promising bioactive preparation «thiomebicar» (2,4,6,8-tetramethyldithioglycoluril) have been estimat-ed. A comparative analysis of the obtained data with those for the well-known pharmatseuti-cal «mebicar» (2,4,6,8-tetramethylglycoluril), being a full carbonyl-substituted analogue pos-sessing the pronounced tranquilizing effect, has been carried.

Key words: 2,4,6,8-tetramethyldithioglycoluril, melting point, fusion heat, sublimation standard en-thalpy

ЛИТЕРАТУРА

2016, Т. 59, № 12, Стр. 40-44
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